Antioxidant activity and the potential for cholesterol-lowering of phenolic extract of Morus alba, Morus multicaulis, and Morus laevigata leaves from Yunnan (China)

作者：Zhang, Yanxin; Du, Wei; Zhang, Xuewen; Zhao, Hongmu; Wang, Yanhui^*

来源：Journal of Food Biochemistry, 2017, 41(1): e12339.

DOI：10.1111/jfbc.12339

• antioxidant activity
• cholesterol-lowering capacity
• Mulberry species
• phenolic composition

The free and bound phenolic extracts of leaves from three mulberry species, Morus alba Linn., M. multicaulis Perr., and M. laevigata Wall. from Yunnan (China), were evaluated for the first time to examine their phenolic composition, antioxidant, and cholesterol-lowering capacity in HepG2 cells. The result showed that the total phenolic content of six extracts were ranged from 0.54 to 17.63 mg GAE/g DW, and the total flavonoids content varied from 0.52 to 35.62 mg RE/g DW. Chlorogenic acid, Rutin, and Catechin were the main compounds in the selected mulberries. The antioxidant properties in a positive correlation with the phenolic contents of mulberries were exhibited. The free phenolic extract of M. multicaulis Perr. significantly decrease the intracellular cholesterol content in HepG2 cells. In a word, the free phenolic extracts of M. multicaulis Perr. could be used as for further nutritional studies for cholesterol-lowering in the food and medicine industries.

• 出版日期2017-2
• 单位云南省农业科学院