A novel pyrene-2-(pyridin-2-ylmethylsulfanyl) ethylamine based turn-on dual sensor for Al3+: experimental and computational studies

作者：Bhowmick Rahul; Dolai Malay; Alam Rabiul; Mistri Tarun; Katarkar Atul; Chaudhuri Keya; Ali Mahammad^*

来源：RSC Advances, 2014, 4(79): 41784-41792.

DOI：10.1039/c4ra06018k

A new pyrene based highly sensitive and selective Al3+ sensor, pyrene-2-(pyridin-2-ylmethylsulfanyl)-ethylamine (PP), was found to exhibit a turn-on fluorescence enhancement (FE) as high as 7.4 fold with K-d(2.55 +/- 0.10) x 10(-4) M and n = 1. This probe binds reversibly with Al3+ in the presence of H(2)EDTA(2-), both under intra-and exctracellular conditions. LOD determined by 3s methods was found to be 15 nM while LOQ = 52.8 nM. The tentative coordination environment in the Al3+-PP complex was delineated by DFT calculations both on the free ligand and complex. The TDDFT calculations reveal spectral features comparable to the experimental ones.

• 出版日期2014