An Efficient Method on Nitration of Eugenol Using NH4NO3 and KHSO4

作者:Sudarma I M*; Wazni N; Wildawaty N; Yuanita E; Suana I W
来源:Asian Journal of Chemistry, 2014, 26(1): 173-175.
DOI:10.14233/ajchem.2014.15367

摘要

The main objective of this research was to find new method for the synthesis of nitro-eugenol. Nitro-eugenol is of considerable importance in the production of other fine chemicals such as amino-eugenol for further chemical synthesis and has also been reported to possess antibacterial, antioxidant and anticancer properties. In an attempt to synthesize nitro-eugenol in high yield, some different nitration methods of eugenol have been applied. An efficient method using NH4NO3 in the presence of KHSO4 as a catalyst has been found to give nitro-eugenol in good yield.

  • 出版日期2014-1