APPLICATION OF TISSUE MICROARRAY TECHNIQUE (TMA) IN NEOPLASTIC MARKERS STUDIES ON BREAST CANCERS

作者：Kobierzycki Christopher^*; Malinska Agnieszka; Dziegiel Piotr

来源：Postepy Biologii Komorki, 2012, 39(3): 519-530.

• tissue microarrays
• TMA
• proliferation markers
• breast cancer

The tissue microarray technique (TMA) was presented for the first time over 15 years ago. Since then, its use grows steadily and preparations achieved with its help meet all standards required to conduct advanced research. In this article methods for creating classic TMA and the alternative solutions proposed by some authors will be shown. An overview of research conducted with the use of TMA will be presented, concerning studies for new markers of tumor cell proliferation in breast cancers. Moreover further possibilities and difficulties arising from the use of this modem method will be discussed. This article aims to draw attention to the possibility of more frequent use of tissue microarray technique for diagnostic and research conducted in Poland.

• 出版日期2012