Duration of preceding hypertension is associated with prolonged length of ICU stay

作者：Sanders Julie S^*; Skipworth James R A; Cooper Jackie A; Brull David J; Humphries Steve E; Mythen Michael; Montgomery Hugh E

来源：International Journal of Cardiology, 2012, 157(2): 180-184.

DOI：10.1016/j.ijcard.2010.12.011

• Coronary artery bypass graft surgery
• Prolonged length of intensive care unit stay
• Prolonged mechanical ventilation
• Pre-operative risk factors
• Hypertension

Background: A substantial proportion of patients suffer prolonged length of intensive care unit stay (PLOS) or prolonged mechanical ventilation (PMV) following coronary artery bypass grafting (CABG). Identifying factors associated with PLOS and PMV would aid in patient risk stratification. We sought to identify the factors associated with PLOS and PMV following CABG.
Methods: Participants were patients undergoing first-time elective CABG. All were observed until discharge and clinical data were collected on a standardized proforma. PLOS and PMV were defined a priori as >2 days and >12 h respectively, based on centre norms.
Results: Of the 439 patients in the study, 105 (23.9%) had PLOS and 111 (25.2%) had PMV. Independent predictors of PMV were age, diabetes, previous myocardial infarction (MI), New York Heart Association (NYHA) class and statin use. The only independent predictor of PLOS was the duration of preceding hypertension.
Conclusion: The factors associated with PMV and PLOS in our study are easily attainable, routine clinical details and may be built into bed management algorithms. Confirmation of the association of preceding hypertension and subsequent investigation of the possible mechanism mediating this association, is suggested.

• 出版日期2012-5-31