A compact laser-based spectrometer for detection of C2H2 in exhaled breath and HCN in vitro

作者：Marchenko D^*; Neerincx A H; Mandon J; Zhang J; Boerkamp M; Mink J; Cristescu S M; Hekkert S te Lintel; Harren F J M

来源：Applied Physics B: Lasers and Optics , 2015, 118(2): 275-280.

DOI：10.1007/s00340-014-5983-y

We report on the development of a compact prototype near-infrared DBR laser-based spectrometer employing off-axis integrated cavity output spectroscopy. The spectrometer is capable of simultaneous detection of acetylene (C2H2) and CO2 at 1,529.2 nm as well as hydrogen cyanide (HCN) at 1,533.5 nm. The detection limits of 8 ppbv for C2H2 and 80 ppbv for HCN are achieved for the acquisition time of 1 s. The setup has been tested for online measurements of C2H2 in exhaled breath of a smoking subject and HCN resulting from the metabolism of Pseudomonas aeruginosa bacteria in vitro. Further improvements of the performance of the spectrometer are discussed.

• 出版日期2015-2