A Novel Mode of Reactivity for Gold(I): The Decarboxylative Activation of (Hetero) Aromatic Carboxylic Acids

作者：Cornella Josep; Rosillo Lopez Martin; Larrosa Igor^*

来源：Advanced Synthesis & Catalysis, 2011, 353(8): 1359-1366.

DOI：10.1002/adsc.201100109

• aryl-gold(I) species
• decarboxylation
• gold
• halogenation
• homogeneous catalysis
• silver

Gold(I) salts are found to mediate the decarboxylation of a variety of aromatic and heteroaromatic carboxylic acids at significatively lower temperatures (as low as 60 degrees C) than the currently used copper(I) (180-190 degrees C) and silver(I) (80-140 degrees C) systems. In contrast to silver(I)-and copper(I)-mediated decarboxylations, the resulting aryl-gold(I) complexes are stable towards protodemetallation and can be readily isolated.

• 出版日期2011-5