A Microcontinuum Model for Mechanical Properties of Esophageal Tissue: Experimental Methodology and Constitutive Analysis

作者:Sanchez Molina D*; Velazquez Ameijide J; Arregui Dalmases C; Rodriguez D; Quintana V; Shafieian M; Crandall J R
来源:Annals of Biomedical Engineering, 2014, 42(1): 62-72.
DOI:10.1007/s10439-013-0897-0

摘要

Accurate material properties of tissues are a key factor for the improvement of medical procedures and treatments. Experimental data are essential in order to formulate and validate a useful constitutive model for predicting the mechanical behavior of tissues in these procedures. This study develops a comprehensive experimental protocol at multiple length scale levels in order to obtain stress-strain curves for esophagus tissue. This paper compares two different models: a conventional, non-linear elastic model, and a microcontinuum model based on fiber rearrangement. Also, a detailed description of the experimental procedure is provided. While the focus was on esophageal tissues, the experimental procedure and microcontinuum are considered widely applicable to other samples of soft tissue.

  • 出版日期2014-1