A practical guide to neonatal volume guarantee ventilation

作者：Klingenberg C^*; Wheeler K I; Davis P G; Morley C J

来源：Journal of Perinatology, 2011, 31(9): 575-585.

DOI：10.1038/jp.2011.98

• infant
• newborn
• volume-targeted ventilation
• tidal volume
• mechanical ventilation

A recent systematic review and meta-analysis shows that volume-targeted ventilation (VTV) compared with pressure-limited ventilation (PLV) reduce death and bronchopulmonary dysplasia, pneumothorax, hypocarbia and severe cranial ultrasound abnormalities. In this paper, we present published research and our experience with volume guarantee (VG) ventilation, a VTV mode available on the Drager Babylog 8000plus and VN500 ventilators. The VG algorithm measures the expired tidal volume (V-T) for each inflation and adjusts the peak inflating pressure for the next inflation to deliver a V-T set by the clinician. The advantage of controlling expired V-T is that this is less influenced by endotracheal tube leak than inspired V-T. VG ventilation can be used with an endotracheal tube leak up to similar to 50%. Initial set V-T for infants with respiratory distress syndrome should be 4.0 to 5.0 ml kg(-1). The set V-T should be adjusted to maintain normocapnoea. Setting the peak inflating pressure limit well above the working pressure is important to enable the ventilator to deliver the set V-T, and to avoid frequent alarms. This paper provides a practical guide on how to use VG ventilation. Journal of Perinatology (2011) 31, 575-585; doi:10.1038/jp.2011.98; published online 14 July 2011

• 出版日期2011-9
• 单位河北医科大学