摘要

An efficient Sonogashira coupling reaction has been reported using cost effective and easily accessible CuI/trans-1,2-diaminocyclohexane catalytic system. The newly developed method can be successfully employed for the coupling between aryl and heteroaryl halides with terminal acetylenes. Furthermore this methodology can be extended for the one pot synthesis of biologically active benzofuran derivatives.

  • 出版日期2016-8-16