Direct immobilization of enzymes in GaN and InN nanocolumns: The urease case study

作者：Sofikiti N^*; Chaniotakis N; Grandal J; Utrera M; Sanchez Garcia M A; Calleja E; Iliopoulos E; Georgakilas A

来源：Applied Physics Letters, 2009, 95(11): 113701.

DOI：10.1063/1.3227888

In this work, the development of potentiometric urea biosensors through the entrapment of urease enzyme within the cavities of nanocolumnar GaN and InN wurtzite semiconductor substrates, is being described. The biosensing capabilities of these materials are compared with biosensors based on the corresponding flat surfaces, in order to check the increased sensitivity and enzyme stabilization properties expected from the nanocolumns. The obtained results proved that the electrochemically active nanocolumns serve both as highly sensitive transducer, as well as stabilizing nanoenvironment within which urease retains its catalytic activity for a prolonged period of time.

• 出版日期2009-9-14