Novel developments in the multidimensional characterization of segmented copolymers

作者：Malik Muhammad Imran; Pasch Harald^*

来源：Progress in Polymer Science, 2014, 39(1): 87-123.

DOI：10.1016/j.progpolymsci.2013.10.005

• Segmented copolymers
• HPLC of copolymers
• Spectroscopy of copolymers
• Multidimensional chromatography
• Hyphenated techniques
• Structure-property relationships

Controlled radical polymerization (CRP) provides the polymer chemist with the ability to produce tailor-made polymers with controlled molar masses, molar mass distributions, chemical compositions and macromolecular architectures. Segmented copolymers can be synthesized having polymer segments arranged in a linear fashion (linear block copolymers), however, polymer segments can also be attached to pre-synthesized macromolecules or to multifunctional core molecules to produce branched (graft) copolymers, polymer stars or dendrimers. Although there are many ways to control the chain growth and the architecture of the target macromolecules, side reactions cannot be completely avoided. Accordingly, even with CRP, obtained products exhibit chemical composition and topology distributions along with the molar mass distribution. %26lt;br%26gt;In this review article, recent developments in multidimensional characterization of segmented copolymers are presented. Liquid chromatography (LC) is the most widely used and versatile polymer fractionation technique to address different aspects of copolymer heterogeneity. The potential and limitations of different modes of liquid chromatography of polymers (size exclusion chromatography, different modes of interaction chromatography) and spectroscopic techniques (FTIR, NMR, and MALDI-TOF-MS) are elaborated. Possible method combinations including comprehensive two-dimensional LC and the hyphenation of various modes of LC with spectroscopic techniques are discussed. Advantages and limitations of various off-line and on-line approaches to method hyphenation are highlighted. Examples from recent literature with special focus on segmented copolymers (e.g. block, graft, miktoarm, multibranched or star copolymers) will be reviewed.

• 出版日期2014-1