A New Bis-Labdanic Diterpene from the Rhizomes of Alpinia pahangensis

作者:Sivasothy Yasodha; Ibrahim Halijah; Paliany Audra Shaleena; Alias Siti Aisyah; Nor Nurur Raudzah Md; Awang Khalijah*
来源:Planta Medica, 2013, 79(18): 1775-1780.
DOI:10.1055/s-0033-1351075

摘要

The rhizomes of Alpinia pahangensis yielded a new bis-labdanic diterpene for which the name pahangensin C (1) was proposed along with twelve known analogues (2-13). The structure of 1 was elucidated via spectroscopic methods including 1D and 2D NMR techniques and LCMS-IT-TOF analysis. Compounds 2 and 12 were isolated for the first time from the genus Alpinia. This is the second occurrence of compounds 2 and 12 in the Zingiberaceae family. Selected analogues exhibited moderate to strong inhibitory activity against Staphylococcus aureus and Bacillus cereus.

  • 出版日期2013-12