Hg(II)-coordination by sugar-acids: Role of the hydroxy groups

作者：Ferrari E; Grandi R; Lazzari S; Saladini M^*

来源：Journal of Inorganic Biochemistry, 2005, 99(12): 2381-2386.

DOI：10.1016/j.jinorgbio.2005.09.005

• sugar acids
• metal complexes
• galacturonic acid
• glucuronic acid
• glucosaminic acid

A solution study on the ability of some derivatised sugars [glucuronic acid (GluA), galacturonic acid (GalA) and glucosaminic acid (GlNA)] to complex the Hg(II) ion is reported. The stability constants of the complex species were determined by potentiometric measurements while H-1 NMR experiments allow to define the coordination sites of sugar molecules. GluA coordinates the metal ion through the carboxylic oxygen and the O-4 hydroxyl group and is found to form more stable complexes with respect to GalA in which metal ligation is from the carboxylic oxygen and the O-5 ring oxygen. GlNA forms stable complexes chelating Hg(II) ion through carboxylic oxygen and the a-amino group. The ternary 2,2'-bipyridine containing systems were also investigated by means of potentiometric studies. The ML2 complexes were also isolated in the solid state and characterised by IR spectroscopy.

• 出版日期2005-12