Fabrication of Human IgG Sensors Based on Porous Silicon Interferometer Containing Bragg Structures

作者:Cho Bomin; Lee Bo Yeon; Kim Hee Cheol; Woo Hee Gweon; Sohn Honglae*
来源:Journal of Nanoscience and Nanotechnology, 2012, 12(5): 4159-4162.
DOI:10.1166/jnn.2012.5921

摘要

A simply modified biosensor based on protein A-modified distributed Bragg reflectors (DBR) porous silicon (PSI) chip for the detection of human immunoglobin G (IgG) are developed. The fabrication, optical characterization, and surface derivatization of DBR PSI are investigated. The sensor system studied consist of multi-layer of porous silicon modified with protein-A. The sensor is operated by the measurement of the reflection peak in the white light reflection spectrum. Molecular binding is detected as a shift in wavelength of reflection peaks.

  • 出版日期2012-5