A Comprehensive Review of the Structure Elucidation and Biological Activity of Triterpenoids from Ganoderma spp.

作者:Xia Qing; Zhang Huazheng; Sun Xuefei; Zhao Haijuan; Wu Lingfang; Zhu Dan; Yang Guanghui; Shao Yanyan; Zhang Xiaoxue; Mao Xin; Zhang Lanzhen*; She Gaimei
来源:Molecules, 2014, 19(11): 17478-17535.
DOI:10.3390/molecules191117478

摘要

Ganoderma triterpenes (GTs) are the major secondary metabolites of Ganoderma lucidum, a traditional Chinese medicine, popularly used for complementary cancer therapy. GTs are lanostane-tetracyclic triterpenes. They have been reported to possess anti-tumor, anti-inflammation, antioxidant, antimicrobial and blood fat reducing effects. To date, 316 GTs have been found and their similar chemical structures have proved difficult to elucidate. This paper compiles 316 naturally occurring triterpenes from Ganoderma based on the literature published through January 2013 along with their structures, physiological activities and C-13-NMR spectral data.