Cerebral perfusion in stroke-like migraine attacks after radiation therapy syndrome

作者:Olsen Abby L; Miller Julie J; Bhattacharyya Shamik; Voinescu P Emanuela; Klein Joshua P*
来源:Neurology, 2016, 86(8): 787-789.
DOI:10.1212/WNL.0000000000002400

摘要

Stroke-like migraine attacks after radiation therapy (SMART) syndrome is characterized by transient, focal neurologic symptoms occurring years after radiation,(1) with focal or regional cortical thickening and gadolinium enhancement on MRI in the area of brain exposed to radiation. The pathophysiology of the syndrome is not well-understood. We present 2 patients with recurrent attacks of SMART syndrome with increased cerebral blood volume in affected regions and abnormal vascular reactivity on transcranial Doppler ultrasound, suggesting a potential mechanism.

  • 出版日期2016-2-23