SOLID STATE STUDY OF THE INCLUSION COMPOUNDS OF ALPHA-, BETA- CYCLODEXTRIN WITH D-, L-TRYPTOPHAN ISOMERS

作者：Neacsu Andreea D; Neacsu Ana; Contineanu Iulia; Munteanu Gabriel; Tanasescu Speranta

来源：Romanian Journal of Chemistry, 2013, 58(11-12): 863-870.

• cyclodextrin
• tryptophan
• complex
• bonds
• energy

The solid inclusion complexes of alpha- and beta-cyclodextins (CD) with stereo isomeric tryptophan (Trp) amino acids (L-tryptophan and D-tryptophan) were studied by using Differential Scanning Calorimetry (DSC), Fourier Transform Infrared Spectroscopy (FT-IR) and simulation methods. The data reveal that selective inclusion complex formation of alpha- and beta-cyclodextrins with L-tryptophan and D-tryptophan amino acids takes place. The correlation of the experimental and theoretical data shows that the complexation between the tryptophan and cyclodextrin could be explained by geometrical differences giving higher stability for the systems including beta-cyclodextrin.

• 出版日期2013-12