An outbreak of highly pathogenic H5N1 avian influenza in Korea, 2008

作者：Kim Hye Ryoung^*; Park Choi Kyu; Lee Youn Jeong; Woo Gye Hyeong; Lee Kyoung Ki; Oem Jae Ku; Kim Seong Hee; Jean Young Hwa; Bae Yu Chan; Yoon Soon Seek; Roh In Soon; Jeong Ok Mi; Kim Ha Young; Choi Jeong Soo; Byun Jae Won; Song Yun Kyung; Kwon Jun Hun; Joo Yi Seok

来源：Veterinary Microbiology, 2010, 141(3-4): 362-366.

DOI：10.1016/j.vetmic.2009.09.011

• 2 3 2 Cade
• HPAI
• H5N1
• Influenza A virus

In spite of intensive surveillance programs for the control of HPAI, an outbreak of highly pathogenic avian influenza (HPAI) H5N1 in Korea in April 2008 caused serious damage to poultry farms, as did previous outbreaks in 2003/2004 and 2006/2007 Six viruses were selected from the Korean 2008 isolates for genetic analysis, and all eight gene segments from each of the influenza viruses were sequenced. A phylogenetic analysis showed that all of the viruses were of the same virus type and that the hemagglutinin (HA) gene was clustered with that of clade 2 3 2 viruses. However, the internal and neuraminidase (NA) genes were closely related to those of the clade 2.3.4 viruses (recent human and bird isolates from Southeast Asia).

• 出版日期2010-3-24