An enterovirus from a captive primate in China

作者：Wang, Xiaochun; Shao, Shihe; Wang, Hua; Shen, Quan; Yang, Shixing; Zhang, Wen^*

来源：SpringerPlus, 2016, 5(1): 1281.

DOI：10.1186/s40064-016-2966-y

• Enterovirus
• EV-J
• Non-human primate
• Phylogenetic analysis
• Viral metagenomics

Background: Enteroviruses (EVs) are a genetically and antigenically diverse group of viruses infecting humans and a variety of animals including non-human primates (NHPs). The present study was to investigate EVs in the fecal samples from captive NHPs in zoos in China using classic RT-PCR and viral metagenomics methods.
Findings: An EV strain was detected in a fecal sample collected from a captive NHP of a zoo in eastern China. The complete genome of this EV strain (named Sev-nj1) was determined and characterized. Sequence analysis indicated Sev-nj1 shared the highest sequence identity (75.6 %) with an EV-J strain, Poo-1, based on the complete genome. Phylogenetic analysis showed Sev-nj1 clustered with the other EV-J strains, forming a separate clade.
Discussion: According to the genetic distance-based criteria, Sev-nj1 belonged to a new type within the species EV-J. This is the first study detecting EV-J from a NHP in China, which will be helpful for the future epidemiology study of EVs in NHPs.

• 出版日期2016-8-8
• 单位江苏大学