Regioselective nucleophilic opening of epoxides and aziridines under neutral conditions in the presence of beta-cyclodextrin in water

作者：Srinivas B; Kumar V Pavan; Sridhar R; Surendra K; Nageswar Y V D; Rao K Rama^*

来源：Journal of Molecular Catalysis A: Chemical , 2007, 261(1): 1-5.

DOI：10.1016/j.molcata.2006.07.040

• epoxide
• sodium cyanide
• beta-hydroxy nitrile
• N-tosyl aziridines
• beta-amino alcohols
• beta-cyclodextrin
• supramolecular catalysis water

A variety of beta-hydroxy nitriles and beta-amino alcohols have been synthesized by the regioselective ring opening of epoxides and aziridines under neutral and aqueous conditions in the presence of beta-cyclodextrin in good yields.

• 出版日期2007-1-2