A mild and efficient method for the conversion of aldehydes into nitriles and thiols into disulfides using an ionic liquid oxidant

作者：Hosseinzadeh Rahman^*; Golchoubian Hamid; Nouzarian Mahboobe

来源：Research on Chemical Intermediates, 2015, 41(7): 4713-4725.

DOI：10.1007/s11164-014-1562-4

• Hexamethylene bis(N-methylimidazolium) bis(dichloroiodate)
• Ionic liquid oxidant
• Nitriles
• Disulfides
• Oxidation

A simple, mild and high yielding method for the conversion of various aldehydes to nitriles has been developed using an ionic liquid reagent, hexamethylene bis(N-methylimidazolium) bis(dichloroiodate) (HMBMIBDCI), in combination with aqueous ammonia in CH3CN at room temperature. Moreover, the treatment of aromatic and aliphatic thiols with HMBMIBDCI resulted in the corresponding disulfides in solvent-free condition at room temperature.

• 出版日期2015-7