A novel ratiometric fluorescent probe based on 1, 8-naphthalimide for the detection of Ho3+ and its bioimaging

作者:Zhang, Huifang; Liu, Tao; Yin, Caixia*; Wen, Yin; Chao, Jianbin; Zhang, Yongbin; Huo, Fangjun*
来源:Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy , 2017, 174: 230-235.
DOI:10.1016/j.saa.2016.11.039

摘要

A ratiometric fluorescent probe for the detection of Ho3+ in DMSO-aqueous medium was designed and synthesized based on 1, 8-naphthalimide. The probe displayed response to Ho3+ with a fluorescence decrease at 512 nm and enhancement at 480 nm, accompanying with a distinct fluorescence change from bright yellow green to cyan. Besides, the probe exhibited a lower detection limit (6 x 10(-8) M) and could be used in intracellular fluorescence imaging. To the best of the knowledge, it was the first ratiometric fluorescent probe for Ho3+ detection. This probe was expected to be a useful tool for further elucidating the roles of Ho3+ in materials, biology and environment.