Adaptation of Hydrogenobacter thermophilus toward oxidative stress triggered by high expression of alkyl hydroperoxide reductase

作者：Sato Yuya; Arai Hiroyuki; Igarashi Yasuo; Ishii Masaharu^*

来源：Bioscience Biotechnology and Biochemistry, 2014, 78(9): 1619-1622.

DOI：10.1080/09168451.2014.921559

• ferriperoxin
• rubrerythrin
• ahpC
• oxidative stress defense

Ferriperoxin is a novel peroxidase essential for aerobiosis of Hydrogenobacter thermophilus. Although the ferriperoxin-deficient mutant (Delta fpx) was unable to grow aerobically, a suppressor mutant capable of aerobic growth was obtained after long aerobic cultivation. The alkyl hydroperoxide reductase gene was significantly upregulated in the suppressor mutant, indicating that the enzyme counteracts oxidative stress in the absence of ferriperoxin.

• 出版日期2014-9