Nosocomial Outbreak of Drug-Resistant Streptococcus pneumoniae Serotype 9V in an Adult Respiratory Medicine Ward

作者：Jauneikaite Elita; Khan Orakzai Zareena; Kapatai Georgia; Bloch Susannah; Singleton Julie; Atkin Sara; Shah Victoria; Hatcher James; Samarasinghe Dunisha; Sheppard Carmen; Fry Norman K; Satta Giovanni^*; Sriskandan Shiranee^*

来源：Journal of Clinical Microbiology, 2017, 55(3): 776-782.

DOI：10.1128/JCM.02405-16

• Streptococcus pneumoniae
• nosocomial infections
• bacteremia
• pneumonia
• serotype 9V

Streptococcus pneumoniae infections arising in hospitalized patients are often assumed to be sporadic and linked to community acquisition. Here, whole-genome sequencing was used to demonstrate nosocomial acquisition of antimicrobial-resistant sequence type 156 (ST156) serotype 9V S. pneumoniae in 3 respiratory patients that resulted in two bacteremias and one lower respiratory tract infection. Two of the cases arose in patients who had recently been discharged from the hospital and were readmitted from the community. Nosocomial spread was suspected solely because of the highly unusual resistance pattern and case presentations within 24 h of one another. The outbreak highlights the potential for rapid transmission and the short incubation period in the respiratory ward setting.

• 出版日期2017-3