科研之友
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摘要
Hypertensive urgency/emergency is a common and potentially life threatening condition that is characterised by a rapid and strong increase in blood pressure. It is estimated that hypertensive urgencies/emergencies account for 25 % of all patient visits in the medical section of emergency departments. Between 24 September 2007 and 06 September 2008, we investigated 195 persons with hypertensive events who were admitted to the emergency unit of the University Clinic St. Josef Hospital in Bochum. After stabilization of blood pressure, the patients were sent to the ward for further evaluation. Aldosterone, renin, and cortisol levels were monitored during the first 24 hours. Blood was taken at 8 am after 2 hours in supine position and after mobilization at 10 am. Meteorological data at the time of admission were analyzed for potential associations with the temporary accumulation of hypertensive events. The meteorological parameters were air temperature TA, relative humidity RH, air pressure P, and sunshine duration SD, observed at the meteorological station in Dusseldorf (airport). In addition, perceived temperature PT was calculated and included in the analysis. First results indicate that the hypertensive events occurred on days when TA departed on average -0.28 K (95 % confidence interval: -0.59 to -0.03 K) and PT deviated on average -0.43 K (-0.82 to -0.04) from the respective values of the preceding day. On days without hypertensive events TA was on average 0.21 (-0.08 to 0.49) and PT was on average 0.32 K (-0.04 to 0.68) higher than on the day before. Days with and days without cases of hypertensive events were, with respect to the daily TA and PT changes, significantly different (TA: p = 0.012; PT: p = 0.003). On days with lower PT than on the previous day the probability of a hospital admission due to a hypertensive event was more than twice as high as on days with higher PT than on the day before. These first results indicate a potential relationship between the ability to adapt to cooler weather and hypertensive urgencies/emergencies.
- 出版日期2011-10
