Comparison of retinal nerve fiber layer thickness between normal and patients with high myopia after phacoemulsification surgery

作者：Qu, Shen; Lin, Meng-Zhen; Niu, Yun-Li; Bi, Yan-Long; Liu, Xin; Li, Hou-Shuo; Rong, Ao^*

来源：International Journal of Clinical and Experimental Medicine, 2016, 9(10): 20095-20099.

• Retinal nerve fiber layer
• high myopia
• phacoemulsification
• optical coherence tomography

Objective: To compare the change of retinal nerve fiber layer thickness between normal and patients with high myopia in the short term after phacoemulsification combined with intraocular lens implantation. Methods: An analysis of phacoemulsification and intraocular lens implantation in 52 eyes of 46 patients from September 2013 to December 2013 in Tongji Hospital, measured the retinal nerve fiber layer thickness with optical coherence tomography, and compared the changes of RNFL thickness at different time after surgery with before operation in two groups. Results: Before surgery, the mean retinal nerve fiber layer thickness value was 94.43 +/- 9.35 mu m in simple age-related cataract group, compared with high myopia group of 90.68 +/- 10.15 mu m, there was statistical difference (t=-3.653, P<0.001). The first postoperative day, there was no change of the retinal nerve fiber layer thickness in both groups (94.42 +/- 9.15 mu m and 91.32 +/- 10.06 mu m). From the first postoperative week, the retinal nerve fiber layer thickness began to thickening, the values upped to maximum of 100.09 +/- 7.57 mu m and 100.25 +/- 10.25 mu m in two groups, and compared with preoperation, there was significant statistical differences in both groups (t=-5.384, t=-4.844, P<0.001). To the sixth postoperative month, the optic disc edema reduced gradually, the retinal nerve fiber layer thickness became thinning. Conclusion: Phacoemulsification surgery perhaps damages the retinal nerve fiber layer, especially for high myopia patients.

• 出版日期2016
• 单位贵州省人民医院; 同济大学