A Resumable Fluorescent Probe BHN-Fe3O4@SiO2 Hybrid Nanostructure for Fe3+ and its Application in Bioimaging

作者：Zhou, Xi; Wang, Yujiao; Peng, Qi; Liu, Weisheng^*

来源：Nanoscale Research Letters, 2017, 12(1): 629.

DOI：10.1186/s11671-017-2392-2

• Fluorescent probe
• Resumable
• Hybrid nanostructure
• Fe3+
• Bioimaging

A multifunctional fluorescent probe BHN-Fe3O4@SiO2 nanostructure for Fe3+ was designed and developed. It has a good selective response to Fe3+ with fluorescence quenching and can be recycled using an external magnetic field. With adding EDTA (2.5 x 10(-5) M) to the consequent product Fe3+-BHN-Fe3O4@ SiO2, Fe3+ can be removed from the complex, and its fluorescence probing ability recovers, which means that this constituted on-off type fluorescence probe could be reversed and reused. At the same time, the probe has been successfully applied for quantitatively detecting Fe3+ in a linear mode with a low limit of detection 1.25 x 10(-8) M. Furthermore, the BHN-Fe3O4@ SiO2 nanostructure probe is successfully used to detect Fe3+ in living HeLa cells, which shows its great potential in bioimaging detection.

• 出版日期2017-12-19
• 单位功能有机分子化学国家重点实验室; 兰州大学