A case of hypertrophic cranial pachymeningitis associated with invasive Aspergillus mastoiditis

作者:Okada Masahiro*; Hato Naohito; Okada Yoko; Sato Eriko; Yamada Hiroyuki; Hakuba Nobuhiro; Gyo Kiyofumi
来源:Auris Nasus Larynx, 2015, 42(6): 488-491.
DOI:10.1016/j.anl.2015.04.009

摘要

We report a rare case of hypertrophic cranial pachymeningitis (HCP) associated with invasive Aspergillus mastoiditis. A 63-year-old man with diabetes mellitus underwent mastoidectomy because of chronic discharge from his left ear. The mastoidectomy was unsuccessful in resolving purulent otorrhea; moreover, 7 months later, the patient developed left abducens nerve palsy. Magnetic resonance imaging revealed HCP at the left middle cranial fossa. Although the pathogen could not be identified, an Aspergillus infection was considered based on elevated serum beta-D-glucan and a positive Aspergillus antigen test result. Voriconazole treatment resolved diplopia and left otorrhea and dramatically improved HCP.

  • 出版日期2015-12