Determination of antioxidants in cosmetics by micellar electrokinetic capillary chromatography with electrochemical detection

作者：Guan YQ; Chu QC; Fu LA; Ye JN^*

来源：Journal of Chromatography A, 2005, 1074(1-2): 201-204.

DOI：10.1016/j.chroma.2005.03.063

• cosmetics
• antioxidants
• micellar electokinetic capillary chromatography
• electochemical detection

A new and efficient method for the determination of antioxidants [Propyl gallate (PG), tert-butylhydroquinone (TBHQ), butylated hydroxyanisole (BHA), and butylated hydroxytoluene (BHT)] in cosmetics has been established by using micellar electrokinetic capillary chromatography with electrochemical detection (MECC-ED). Under the optimum conditions of the method, all analytes were successfully separated within 13 min at the separation voltage of 18 kV in a 20 mmol/L borate running buffer (pH 7.4) containing 25 mmoUL sodium dodecyl sulfate. The excellent linearity was obtained in the concentration range from 5.0 x 10(-4) to 2.0 x 10(-6) mol/L and the detection limits (SIN= 3) of PG, TBHQ, BHA, and BHT range from 3 x 10(-7) to 3 x 10(-1) mol/L.

• 出版日期2005-5-13
• 单位华东师范大学