摘要

This paper presents a journey through the known and the presumed history of two important mycotoxicoses which played an important role in the history of mankind before aflatoxins were discovered: (1) ergotism, also known as St. Anthony's fire or Holy Fire, linked to the consumption of cereals (especially rye) contaminated by the hallucinogenic and vasoconstrictor alkaloids produced by the Claviceps purpurea ergot, whose presence in Europe during the Middle Ages was considered epidemic, and (2) the so-called alimentary toxic aleukia (also known by its English acronym ATA), caused by the trichothecenes produced by Fusarium sporotrichioides and Fusarium poae, which devastated a large part of Russia shortly before the characterisation of the toxins of Aspergillus flavus.

  • 出版日期2011-5