Drosophila Ten-a is a maternal pair-rule and patterning gene (Retracted article. See vol. 129, pg. 73, 2012)

作者：Rakovitsky Nadya; Buganim Yosef; Swissa Torner; Kinel Tahan Yael; Brenner Shirly; Cohen Malkiel A; Levine Anna; Wides Ron^*

来源：Mechanisms of Development, 2007, 124(11-12): 911-924.

DOI：10.1016/j.mod.2007.08.003

• segmentation
• Odz/Tenm genes
• signal transduction
• metamerism

The Ten-a gene of Drosophila melanogaster encodes several alternative variants of a full length member of the Odz/Tenm protein family. A number of Ten-a mutants created by inexact excisions of a resident P-element insertion are embryonic lethal, but show no pair-rule phenotype. In contrast, these mutants, and deficiencies removing Ten-a, do enhance the segmentation phenotype of a weak allele of the paralog gene odz (or Ten-m) to the odz amorphic phenotype. Germ line clone derived Ten-a(-) embryos display a pair-rule phenotype which phenocopies that of odz. Post segmentation eye patterning phenotypes of Ten-a mutants establish it as a pleiotropic patterning co-partner of odz.

• 出版日期2007-12