A comparison of non-HDL and LDL cholesterol goal attainment in a large, multinational patient population: The Lipid Treatment Assessment Project 2

作者：Santos Raul D^*; Waters David D; Tarasenko Lisa; Messig Michael; Jukema J Wouter; Chiang Cheng Wen; Ferrieres Jean; Foody JoAnne M

来源：Atherosclerosis, 2012, 224(1): 150-153.

DOI：10.1016/j.atherosclerosis.2012.06.052

• Non-HDL cholesterol
• LDL-cholesterol
• Coronary heart disease
• Risk factors
• Triglycerides

Objective: This study evaluated the success in attaining non-HDL-cholesterol (non-HDL-C) goals in the multinational L-TAP 2 study. %26lt;br%26gt;Methods: 9955 patients %26gt;= 20 years of age with dyslipidemia on stable lipid-lowering therapy were enrolled from nine countries. %26lt;br%26gt;Results: Success rates for non-HDL-C goals were 86% in low, 70% in moderate, and 52% in high-risk patients (63% overall). In patients with triglycerides of %26gt;200 mg/dL success rates for non-HDL-C goals were 35% vs. 69% in those with %26lt;= 200 mg/dL (p %26lt; 0.0001). Among patients attaining their LDL-C goal, 18% did not attain their non-HDL-C goal. In those with coronary disease and at least two risk factors, only 34% and 30% attained respectively their non-HDL-C and LDL-C goals. Rates of failure in attaining both LDL-C and non-HDL-C goals were highest in Latin America. %26lt;br%26gt;Conclusions: Non-HDL-C goal attainment lagged behind LDL-C goal attainment; this gap was greatest in higher-risk patients.

• 出版日期2012-9