A supramolecular self-assembly strategy for upconversion nanoparticle bioconjugation

作者:Sun, Yulong; Zhang, Wenjing; Wang, Baoming; Xu, Xiaoxue; Chou, Joshua; Shimoni, Olga*; Ung, Alison T.; Jin, Dayong*
来源:Chemical communications, 2018, 54(31): 3851-3854.
DOI:10.1039/c8cc00708j

摘要

An efficient surface modification for upconversion nanoparticles (UCNPs) is reported via supramolecular host-guest self-assembly. Cucurbit[7]uril (CB) can provide a hydrophilic surface and cavities for most biomolecules. High biological efficiency, activity and versatility of the approach enable UCNPs to be significantly applied in bio-imaging, early disease detection, and bio-sensing.