A pyridoxal-based dual chemosensor for visual detection of copper ion and ratiometric fluorescent detection of zinc ion

作者：Qu Lijun; Yin Caixia^*; Huo Fangjun; Chao Jianbin; Zhang Yongbin; Cheng Fangqin

来源：Sensors and Actuators B: Chemical , 2014, 191: 158-164.

DOI：10.1016/j.snb.2013.09.114

• Pyridoxal-based
• Copper ions
• Zinc ions
• Naked eye
• Ratiometric fluorescence

A pyridoxal-based fluorescein derivative was synthesized by reacting fluorescein hydrazide and pyridoxal hydrochloride in ethanol and characterized by NMR, ESI-MS and X-ray. The optical properties of probe were investigated in methanol: HEPES solution. The probe displayed selectivity for Cu2+, which was characterized using UV-visible spectroscopy. Moreover, the process also allowed visual detection of Cu2+ by a colorless to yellow change. In contrast, selectivity toward Zn2+ was determined in the emission spectra showing OFF-ON type fluorescence changes from colorless to green. This represents the first reported pyridoxal-based sensor capable of detecting both Cu2+ and Zn2+ using two different modes. Furthermore, it can be used to bioimaging.

• 出版日期2014-2
• 单位山西大学; 中国科学院长春应用化学研究所