Auditory evoked potentials and multiple sclerosis

作者：Matas Carla Gentile^*; de Andrade Matas Sandro Luiz; Salzano de Oliveira Caroline Rondina; Goncalves Isabela Crivellaro

来源：Arquivos de Neuro-Psiquiatria, 2010, 68(4): 528-534.

DOI：10.1590/S0004-282X2010000400010

• auditory evoked potentials
• auditory brain stem evoked potentials
• P300 event-related potentials
• multiple sclerosis

Multiple sclerosis (MS) is an inflammatory, demyelinating disease that can affect several areas of the central nervous system. Damage along the auditory pathway can alter its integrity significantly. Therefore, it is important to investigate the auditory pathway, from the brainstem to the cortex, in individuals with MS. Objective: The aim of this study was to characterize auditory evoked potentials in adults with MS of the remittent-recurrent type. Method: The study comprised 25 individuals with MS, between 25 and 55 years, and 25 age- and gender-matched healthy controls (research and control groups). Subjects underwent audiological and electrophysiological evaluations. Results: Statistically significant differences were observed between the groups regarding the results of the auditory brainstem response and the latency of the Na and P300 waves. Conclusion: Individuals with MS present abnormalities in auditory evoked potentials indicating dysfunction of different regions of the central auditory nervous system.

• 出版日期2010-8