An Efficient Formal Total Synthesis of Cladosporin

作者:Mohapatra Debendra K*; Maity Saurabh; Rao T Srinivasa; Yadav J S; Sridhar B
来源:European Journal of Organic Chemistry, 2013, 2013(14): 2859-2863.
DOI:10.1002/ejoc.201300053

摘要

A highly diasteroselective and efficient approach for the formal total synthesis of cladosporin is described. Cross-metathesis, iodocyclization to construct the trans-2,6-disubstituted dihydropyran ring system, and an AlderRickert reaction to form the aromatic ring were used as the key steps.

  • 出版日期2013-5