MR imaging versus PET/CT for evaluation of pancreatic lesions

作者：Beliao Sara^*; Ferreira Alexandra; Vierasu Irina; Blocklet Didier; Goldman Serge; Metens Thierry; Matos Celso

来源：European Journal of Radiology, 2012, 81(10): 2527-2532.

DOI：10.1016/j.ejrad.2011.11.045

• Pancreatic cancer
• Chronic pancreatitis
• MRI
• FDG-PET/CT

Purpose: To retrospectively determine the diagnostic accuracy of magnetic resonance imaging (MRI) and combined positron emission tomography/computed tomography (PET/CT) in the differential diagnosis of benign and malignant pancreatic lesions.
Materials and methods: Twenty-seven patients (15 women/12 men, mean age 56.5 years) with MR imaging and PET/CT studies performed to differentiate benign and malignant pancreatic lesions were identified between October 2008 and October 2010. Both MR and PET/CT data sets were retrospectively and blindly evaluated by two independent readers (4 readers total) with different degrees of experience, using a visual five-point score system. The results were correlated with final diagnosis obtained by histopathology.
Results: 17 patients had malignant diseases and 10 patients had benign diseases. Depending on the observer, the sensitivity, specificity, positive predictive value and negative predictive value of MRI varied between 88-94%, 50-80%, 75-89% and 71-89% respectively. Sensitivities, specificities, positive predictive values and negative predictive values of PET/CT were 73%, 56%, 73% and 56% respectively. The diagnostic accuracy of MR for the differential diagnosis of pancreatic lesions was 74-89%, compared with 67% for PET/CT. The weighted Cohen's kappa coefficient was 0.47 at MR and 0.53 at PET/CT.
Conclusion: MRI achieved higher sensitivity and specificity in the differential diagnosis of pancreatic lesions.

• 出版日期2012-10