No Decreased Infection Rate When Using Antibiotic-Impregnated Cement in Primary Total Joint Arthroplasty

作者：Zeng Yi; Shen Bin^*; Yang Jing; Zhou Zongke; Kang Pengde; Pei Fuxing

来源：Orthopedics, 2014, 37(12): 839-845.

DOI：10.3928/01477447-20141124-07

• TOTAL HIP-ARTHROPLASTY
• TOTAL KNEE ARTHROPLASTY
• GENTAMICIN BONE-CEMENT
• SIMPLEX-P
• REGISTER
• PROPHYLAXIS
• REPLACEMENT
• IMPACT
• RISK

There has been much debate and controversy about the routine use of antibiotic-impregnated bone cement in primary total joint arthroplasty. The purpose of this study was to undertake a meta-analysis to determine whether the use of antibiotic-impregnated bone cement would reduce the incidence of infection after primary total joint arthroplasty. Of 313 citations identified for screening, 6 trials reporting 26,791 patients were eligible for data extraction and meta-analysis. The authors found no statistically significant difference between antibiotic-impregnated bone cement and plain bone cement in terms of the incidence of infection. The results indicated that the use of antibiotic-impregnated bone cement in primary total joint arthroplasty did not lead to a decrease in the rate of infection.

• 出版日期2014-12
• 单位四川大学