New cyclic tetrapeptide from the coral-derived endophytic bacteria Brevibacterium sp L-4 collected from the South China Sea

作者：Liu, Bing-Xin; Guo, Qiong; Peng, Guang-Tian; He, Xi-Xin; Chen, Xiao-Jie; Lei, Ling-Fang; Deng, Yun; Jun Su, Xian; Zhang, Cui-Xian^*

来源：Natural Product Research, 2016, 30(1): 7-12.

DOI：10.1080/14786419.2015.1026340

• Brevibacterium sp
• L-4
• coral derived endophytic bacteria
• tetrapeptide
• 3-ylidene-2
• 5-piperazinediones

One new cyclic tetrapeptide cyclic-(Tyr-Ala-Leu-Ser) (1) along with four natural compounds firstly obtained 3H-imidazole-4-carboxylic acid (2), 2-methyl-3H-imidazole-4-carboxylic acid (3), 3-ethylidene-6-isopropyl-piperazine-2,5-dione (4), and 3-isobutylidene-6-methyl piperazine-2,5-dione (5) have been isolated from the coral derived endophytic bacteria Brevibacterium sp. L-4 collected from the South China Sea. Their structures were elucidated through spectroscopic techniques including NMR (1D and 2D), MS, and EA, and their relative configurations were also assigned by NMR analysis.

• 出版日期2016-1-2
• 单位广州中医药大学