The effect of non-growth factors on chondrogenic differentiation of mesenchymal stem cells

作者:Zhang, Xiujie; Zhang, Yumin; Wang, Zhiqiang; Li, Qijia; Li, Baoxing*
来源:Cell and Tissue Banking, 2014, 15(3): 319-327.
DOI:10.1007/s10561-013-9403-z

摘要

Chondrogenic differentiation of mesenchymal stem cells (MSCs) in vitro usually requires the presence of growth factors in the culture condition. But many cost-effect methods can successfully fulfill this without addition of these cytokines. This article focuses upon the effect of non-growth factors on the chondrogenic differentiation of MSCs and the concise introduction of the potential mechanism of these methods.