Angiographically Documented Macular Ischemia after Single Bevacizumab for Macular Edema Secondary to Central Retinal Vein Occlusion

作者：Lee Kyou Ho; Kang Eui Chun; Koh Hyoung Jun^*

来源：Yonsei Medical Journal, 2017, 58(3): 676-678.

DOI：10.3349/ymj.2017.58.3.676

• Macular edema
• central retinal vein
• fovea centralis
• bevacizumab
• fluorescein angiography

This report describes a case of angiographically documented foveal avascular zone (FAZ) enlargement after a single intravitreal injection of bevacizumab for macular edema secondary to central retinal vein occlusion (CRVO). A 71-year-old female was treated with an intravitreal bevacizumab injection for macular edema following CRVO. Despite successfully decreased edema one month after injection, the postinjection best-corrected visual acuity immediately decreased from 20/40 to 20/1000 (Snellen equivalent). The FAZ area increased from 0.37 mm(2) to 3.11 mm(2) (8.4-fold increase). While intravitreal anti-vascular endothelial growth factor is effective and should be considered as a first-line treatment for macular edema secondary to CRVO, it may aggravate macular ischemia.

• 出版日期2017-5