Migratory pathways of GABAergic interneurons when they enter the neocortex

作者:Tanaka Daisuke H*; Nakajima Kazunori
来源:European Journal of Neuroscience, 2012, 35(11): 1655-1660.
DOI:10.1111/j.1460-9568.2012.08111.x

摘要

Inhibitory gamma-aminobutyric-acid-containing interneurons play important roles in the functions of the neocortex. During rodent development, most neocortical interneurons are generated in the subpallium and migrate tangentially toward the neocortex. They migrate through multiple pathways to enter the neocortex. Failure of interneuron migration through these pathways during development leads to an abnormal distribution and abnormal functions of interneurons in the postnatal brain. Because of recent discoveries regarding the novel origins and migratory pathways of neocortical interneurons, in this article we review the literature on the migratory pathways of interneurons when they enter the neocortex.

  • 出版日期2012-6