ABO blood group: old dogma, new perspectives

作者:Franchini Massimo*; Liumbruno Giancarlo Maria
来源:Clinical Chemistry and Laboratory Medicine, 2013, 51(8): 1545-1553.
DOI:10.1515/cclm-2013-0168

摘要

Human blood group antigens are glycoproteins and glycolipids expressed on the surface of red blood cells and a variety of human tissues, including the epithelium, sensory neurons, platelets and the vascular endothelium. Accumulating evidence indicate that ABO blood type is implicated in the development of a number of human diseases, including cardiovascular and neoplastic disorders. In this review, beside its physiologic role in immunohematology and transfusion medicine, we summarize the current knowledge on the association between the ABO blood group and the risk of developing thrombotic events and cancers.

  • 出版日期2013-8
  • 单位中国人民解放军空军预警学院