Analyte migration electrospray ionization for rapid analysis of complex samples with small volume using mass spectrometry

作者:Wang Qian; Zhong Hanbin; Zheng Yajun; Zhang Sichun; Liu Xiaoning; Zhang Xinrong; Zhang Xiaoling; Zhang Zhiping*
来源:Analyst, 2014, 139(22): 5678-5681.
DOI:10.1039/c4an01397b

摘要

Complex biological matrices can be effectively removed in the analyte migration process because of their weak solubility in organic solvents. This technique offers other potential advantages, including high-sensitivity and the capability of performing a direct analysis of the components and their metabolites in small-volume raw samples without any pretreatment.