UV Spectrophotometric Method for Determination of the Dissolution Profile of Rivaroxaban

作者:Celebier Mustafa; Kaynak Mustafa Sinan; Altinoz Sacide*; Sahin Selma
来源:Dissolution Technologies, 2014, 21(4): 56-59.
DOI:10.14227/DT210414P56

摘要

Rivaroxaban is an oral anticoagulant that is the first available orally active direct Factor Xa inhibitor. In this study, a UV spectrophotometric method was developed for the determination of rivaroxaban content in pharmaceutical formulations and the amount of rivaroxaban released in tablet dissolution studies. The dissolution profile of rivaroxaban was successfully determined with the validated method.

  • 出版日期2014-11