Non-Apnea Sleep Disorder Increases the Risk of Periodontal Disease: A Retrospective Population-Based Cohort Study

作者：Lee Chun Feng; Lin Ming Chia; Lin Cheng Li; Yen Chia Ming; Lin Kuan Yu; Chang Yen Jung; Kao Chia Hung^*

来源：Journal of Periodontology, 2014, 85(4): E65-E71.

DOI：10.1902/jop.2013.130284

• Cohort studies
• comorbidity
• national health programs
• non-apnea sleep syndrome
• periodontal disease
• sleep disorders

Background: The aim of this study is to determine whether patients with a non-apnea sleep disorder (NA-SD) and comorbidity have an increased risk of periodontal disease. %26lt;br%26gt;Methods: Patients newly diagnosed with NA-SDs in 1997 to 2010 were identified as the study cohort from the Taiwan National Health Insurance database. For each patient with NA-SD, two matched controls without sleep disorders were randomly selected for comparison. %26lt;br%26gt;Results: The overall incidence rate ratio of severe periodontal diseases was 39% higher in the NA-SD cohort than in the comparison cohort (7.93 versus 5.69 per 1,000 person-years), with an adjusted hazard ratio (HR) of 1.36 (95% confidence interval [CI]: 1.30 to 1.43). The effect of NA-SD on the risk of severe periodontal diseases was higher in young and middle-aged patients compared with patients %26gt;65 years of age (%26lt;35 years of age, HR: 1.13, 95% CI: 1.04 to 1.24; 35 to 49 years of age, HR: 1.73, 95% CI: 1.61 to 1.86; 50 to 64 years of age, HR: 1.69, 95% CI: 1.58 to 1.81; 65, HR: [reference] 1.0). %26lt;br%26gt;Conclusion: NA-SD might increase the risk of periodontal disease.

• 出版日期2014-4
• 单位中国医科大学