Microwave-promoted regio- and stereoselective vinylation of heterocyclic thiols

作者:Rajesh Nimmakuri; Sarma Rupam; Prajapati Dipak*
来源:RSC Advances, 2014, 4(15): 7834-7837.
DOI:10.1039/c3ra47417h

摘要

The first stereoselective vinylation of heterocyclic thiols has been reported. Heterocyclic thiols are shown to react efficiently with activated terminal alkynes in an anti-Markovnikov fashion in absence of any catalyst or additive under microwave irradiation to give Z-selective vinyl sulfides.

  • 出版日期2014