Modulators for comprehensive two-dimensional gas chromatography

作者：Tranchida Peter Quinto; Purcaro Giorgia; Dugo Paola; Mondello Luigi^*

来源：TrAC-Trends in Analytical Chemistry, 2011, 30(9): 1437-1461.

DOI：10.1016/j.trac.2011.06.010

• Comprehensive two-dimensional gas chromatography
• Cryogenic modulator
• Flow modulator
• Heart-cutting
• In-line valve system
• Longitudinally-modulated cryogenic system
• Out-line valve system
• Pneumatic modulator
• Re-injection
• Thermal modulator

The analytical benefits of comprehensive two-dimensional gas chromatography (GC x GC) methods have been exploited and emphasized in the past two decades. The unexpectedly complex nature of many real-world samples amenable to GC analysis has been elucidated through the enhanced resolving power of GC x GC. Simple but fundamental devices, called modulators, enable continuous heart-cutting and re-injection, without which GC x GC analysis cannot be achieved. The present review focuses on the history (1991-2010), and present trends and future prospects for GC x GC modulation. We provide detailed descriptions and set out the advantages and the disadvantages of the most significant thermal and pneumatic modulators.

• 出版日期2011-10