New Flavanones from the Leaves of Cryptocarya chinensis and Their Antituberculosis Activity

作者:Chou Tsung Hsien; Chen Jih Jung; Peng Chien Fang; Cheng Ming Jen; Chen Ih Sheng*
来源:Chemistry and Biodiversity, 2011, 8(11): 2015-2024.
DOI:10.1002/cbdv.201000367

摘要

Four new flavanones, cryptoflavanones AD (14, resp.), together with eight known compounds, were isolated from the leaves of Cryptocarya chinensis. The structures of these new compounds were determined by spectral analyses. Among the isolated compounds, pinocembrin (5) and cryptocaryone (6) exhibited antituberculosis activity against Mycobacterium tuberculosis H37Rv strain in vitro with MIC values of 3.5 and 25.0 mu g/ml, respectively.

  • 出版日期2011-11